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Editorial Board
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iii
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The future of clinical research
“Study the past if you would define the future” Confucius (551 BC– 479 BC)
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Edward C. Nemergut
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vii-viii
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High fidelity simulation as a research tool
Medical simulation has grown explosively over the last decade. Simulation is becoming commonplace in clinical education but can also be used as an investigative clinical tool in its own right. There a...
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Keith E. Littlewood
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473-487
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Perioperative effectiveness research using large databases
While the delivery of anaesthesia care is largely a safe process and adverse events are infrequent, they can have devastating consequences for patients and providers when they occur. Given concerns ab...
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Robert E. Freundlich,
Sachin Kheterpal
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489-498
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In silico modelling of physiologic systems
In silico modelling, in which computer models are developed to model a pharmacologic or physiologic process, is a logical extension of controlled in vitro experimentation. It is the natural result of ...
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Richard B. Colquitt,
Douglas A. Colquhoun,
Robert H. Thiele
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499-510
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Improving outcomes in anaesthesiology education on research
For more than 30 years in the United States, we have been lamenting the fate of the clinician-scientist in anaesthesiology. In the past 5 years, attention to the issues has escalated and a number of n...
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Pamela C. Nagle
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511-522
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Research methods for meta-analyses
Meta-analysis uses numerical tools to pool data and to estimate a summary effect size for the comparison of two interventions from a set of randomised controlled trials identified in a systematic revi...
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Nathan Leon Pace
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523-533
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Perioperative comparative effectiveness research
The goal of comparative effectiveness research (CER) is to improve effectiveness, efficacy and efficiency in health care. While CER seems to present a major opportunity to introduce accountability int...
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Stavros G. Memtsoudis,
Melanie C. Besculides
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535-547
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Perioperative genomics
Since the completion of the Human Genome Project 10 years ago, the world has witnessed an incredible progress in human genetics and genomics. This progress was largely driven by the availability of be...
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Peter Nagele
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549-555
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A novel approach to implementation of quality and safety programmes in anaesthesiology
Far too many patients suffer preventable harm from medical errors that add to needless suffering and cost of care. Underdeveloped residency training programmes in patient safety are a major contributo...
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Deborah A. Schwengel,
Bradford D. Winters,
Lauren C. Berkow,
Lynette Mark,
Eugenie S. Heitmiller,
Sean M. Berenholtz
et al.
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557-567
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Best practice & research in anaesthesiology issue on new approaches in clinical research ethics in clinical research
The history of ethics in clinical research parallels the history of abuse of human beings. The Nuremberg Code, Declaration of Helsinki, and the Belmont Report laid the foundations for modern research ...
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Karen J. Schwenzer
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569-582
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Keyword index
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