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Volume 24, Issue 2, Pages 145-155 (June 2010)


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Perioperative modifications of respiratory function

Michelle Duggan, MD, FFARCSI (Consultant Anesthetist)aemail address, Brian P. Kavanagh, MB, FRCPC (Professor)bCorresponding Author Informationemail address

Postoperative pulmonary complications contribute considerably to morbidity and mortality, especially after major thoracic or abdominal surgery. Clinically relevant pulmonary complications include the exacerbation of underlying chronic lung disease, bronchospasm, atelectasis, pneumonia and respiratory failure with prolonged mechanical ventilation. Risk factors for postoperative pulmonary complications include patient-related risk factors (e.g., chronic obstructive pulmonary disease (COPD), tobacco smoking and increasing age) as well as procedure-related risk factors (e.g., site of surgery, duration of surgery and general vs. regional anaesthesia). Careful history taking and a thorough physical examination may be the most sensitive ways to identify at-risk patients. Pulmonary function tests are not suitable as a general screen to assess risk of postoperative pulmonary complications. Strategies to reduce the risk of postoperative pulmonary complications include smoking cessation, inspiratory muscle training, optimising nutritional status and intra-operative strategies. Postoperative care should include lung expansion manoeuvres and adequate pain control.

a Department of Anesthesia, Mayo General Hospital, Castlebar, Co. Mayo, Ireland

b Departments of Anesthesia and Critical Care Medicine, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada

Corresponding Author InformationCorresponding author. Tel.: +1 416 813 6860; Fax: +1 416 813 5315.

PII: S1521-6896(10)00019-4

doi:10.1016/j.bpa.2009.12.001


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