Best Practice & Research Clinical Anaesthesiology
Volume 23, Issue 1 , Pages 51-67 , March 2009

Computer protocols: how to implement

  • A.H. Morris, MD (Professor of Medicine, Adjunct Professor of Biomedical Informatics)

      Affiliations

    • Pulmonary and Critical Care Divisions, Departments of Medicine, LDS Hospital, Intermountain Medical Center, University of Utah School of Medicine, Salt Lake City, UT, USA
    • Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, UT, USA
    • Corresponding Author InformationCorresponding author. Pulmonary/Critical Care Division, Sorenson Heart-Lung Center, 6th Floor, Intermountain Medical Center, 1521 South Cottonwood Street, Murray, UT 84157-7000, USA. Tel.: +1 801 507 4603, +1 801 718 1283 (Mobile); Fax: +1 801 507 4699.
  • ,
  • E. Hirshberg, MD (Assistant Professor of Medicine, Adjunct Assistant Professor of Pediatrics)

      Affiliations

    • Pulmonary and Critical Care Divisions, Departments of Medicine, LDS Hospital, Intermountain Medical Center, University of Utah School of Medicine, Salt Lake City, UT, USA
    • Department of Pediatrics, Primary Children's Medical Center, University of Utah School of Medicine, Salt Lake City, UT, USA
  • ,
  • K.A. Sward, RN, PhD (Assistant Professor of Nursing, Adjunct Assistant Professor of Biomedical Informatics)

      Affiliations

    • Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, UT, USA
    • University of Utah College of Nursing, Salt Lake City, UT, USA

References 

  1. Atkins H. The three pillars of clinical research. British Medical Journal. December 27, 1958;2:1547–1553
  2. Morris A. Algorithm-based decision making. In:  Tobin M editors. Principles and practice of intensive care monitoring. 2nd ed.. New York: McGraw-Hill, Inc.; 1998;p. 1355–1381
  3. Morris A. The importance of protocol-directed patient management for research on lung-protective ventilation. In:  Dreyfuss D,  Saumon G,  Hubamyr R editor. Ventilator-induced lung injury. New York: Taylor & Francis Group; 2006;p. 537–610
  4. Thorens J-B, Kaelin R, Jolliet P, Chevrolet J-C. Influence of the quality of nursing on the duration of weaning from mechanical ventilation in patients with chronic obstructive pulmonary disease. Critical Care Medicine. 1995;23:1807–1815
  5. Wennberg JE, Gittelsohn A. Small area variation analysis in health care delivery. Science. 1973;142:1102–1108
  6. Wennberg JE. Unwarranted variations in healthcare delivery: implications for academic medical centres. British Medical Journal. October 26, 2002;325(7370):961–964
  7. Morris AH. Iatrogenic illness: a call for decision support tools to reduce unnecessary variation. Quality & Safety in Health Care. February 1, 2004;13(1):80–81
  8. Kahneman D, Slovik P, Tversky A. Judgment under uncertainty: heuristics and biases. Cambridge: Cambridge University Press; 1982;
  9. Redelmeier DA, Ferris LE, Tu JV, et al. Problems for clinical judgement: introducing cognitive psychology as one more basic science. CMAJ : Canadian Medical Association Journal. February 6, 2001;164(3):358–360
  10. Redelmeier DA. The cognitive psychology of missed diagnoses. Annals of Internal Medicine. January 18, 2005;142(2):115–120
  11. Miller J. Living systems. New York: McGraw-Hill Book Company; 1978;
  12. Pearl J. Causality: models, reasoning, and inference. Cambridge, UK: Cambridge; 2000;
  13. von Bertalanffy L. General system theory. New York: George Braziller; 1968;
  14. Senn S. Individual response to treatment: is it a valid assumption?. British Medical Journal. October 23, 2004;329(7472):966–968
  15. Lake APJ. Every prescription is a clinical trial. British Medical Journal. December 4, 2004;329(7478):1346
  16. Tversky A, Kahneman D. Availability: a heuristic for judging frequency and probability. In:  Kahneman D,  Slovic P,  Tversky A editor. Judgment under uncertainty: heuristics and biases. Cambridge, UK: Cambridge University Press; 1982;p. 163–178
  17. Jennings D, Amabile T, Ross L. Informal covariation assessment: data-based versus theory-based judgments. In:  Kahneman D,  Slovic P,  Tversky A editor. Judgment under uncertainty: heuristics and biases. Cambridge, UK: Cambridge University Press; 1982;p. 211–230
  18. McDonald CJ. Protocol-based computer reminders, the quality of care and the non-perfectability of man. The New England Journal of Medicine. 1976;295:1351–1355
  19. Abramson NS, Wald KS, Grenvik ANA, et al. Adverse occurrences in intensive care units. JAMA : The Journal of the American Medical Association. 1980;244:1582–1584
  20. Morris AH, Chapman RH, Gardner RM. Frequency of technical problems encountered in the measurement of pulmonary artery wedge pressure. Critical Care Medicine. 1984;12(3):164–170
  21. Morris AH, Chapman RH, Gardner RM. Frequency of wedge pressure errors in the ICU. Critical Care Medicine. 1985;13:705–708
  22. Morris AH. Elimination of pulmonary wedge pressure errors commonly encountered in the ICU. Cardiologia (Italy). 1985;30(10):941–943
  23. Iberti T, Fischer E, Leibowitz M, et al. A multicenter study of physician's knowledge of the pulmonary artery catheter. JAMA : The Journal of the American Medical Association. 1990;264:2928–2932
  24. Iberti TJ, Daily EK, Leibowitz AB, et al. Assessment of critical care nurses' knowledge of the pulmonary artery catheter. The pulmonary artery catheter study group. Critical Care Medicine. 1994;22:1674–1678
  25. Leape L. Error in medicine. JAMA : The Journal of the American Medical Association. 1994;272:1851–1857
  26. Gnaegi A, Feihl F, Perret C. Intensive care physicians' insufficient knowledge of right-heart catheterization at the bedside: time to act?. [see comments] Critical Care Medicine. 1997;25(2):213–220
  27. Wu A, Folkman S, McPhee S, Lo B. Do house officers learn from their mistakes?. JAMA: The Journal of the American Medical Association. 1991;265:2089–2094
  28. Berner ES, Graber ML. Overconfidence as a cause of diagnostic error in medicine. The American Journal of Medicine. 2008;121(5):S2–S23
  29. Arkes H, Hammond K. Judgment and decision making: an interdisciplinary reader. Cambridge: Cambridge University Press; 1986;
  30. Arkes H. Impediments to accurate clinical judgment and plossible ways to minimized their impact. In:  Arkes H,  Hammond K editor. Judgment and decision making: an interdisciplinary reader. Cambridge: Cambridge University Press; 1986;p. 582–592
  31. Morris A. Developing and implementing computerized protocols for standardization of clinical decisions. Annals of Internal Medicine. 2000;132:373–383
  32. In:  Kohn L,  Corrigan J,  Donaldson M editor. To err is human - building a safer health system. Washington, DC: National Academy Press; 1999;
  33. In: Committee on quality of health care in America  editors. Crossing the quality chasm: a new health system for the 21st century. Washington, DC: National Academy Press; 2001;
  34. Leape LL, Berwick DM, Bates DW. What practices will most improve safety? Evidence-based medicine meets patient safety. [comment] JAMA : The Journal of the American Medical Association. Jul 24–31, 2002;288(4):501–507
  35. Kozer E, Seto W, Verjee Z, et al. Prospective observational study on the incidence of medication errors during simulated resuscitation in a paediatric emergency department. British Medical Journal. December 4, 2004;329(7478):1321
  36. Schiff GD, Klass D, Peterson J, et al. Linking laboratory and pharmacy: opportunities for reducing errors and improving care. Archives of Internal Medicine. Apr 28, 2003;163(8):893–900
  37. Runciman WB, Merry A, Tito F. Error, blame and the law in health care - an antipodean perspective. Annals of Internal Medicine. June, 2003;138(12):974–979
  38. Lamb RM, Studdert DM, Bohmer RM, et al. Hospital disclosure practices: results of a national survey. Health Affairs. Mar-Apr, 2003;22(2):73–83(Project Hope)
  39. Zhang J, Patel VL, Johnson TR. Medical error: is the solution medical or cognitive?. Journal of the American Medical Informatics Association. Nov-Dec, 2002;9(6 Suppl.):S75–S77
  40. Phansalkar S, Weir CR, Morris AH, Warner HR. Clinicians' perceptions about use of computerized protocols: a multicenter study. International Journal of Medical Informatics. 2008;77(3):184–193ENG
  41. Hulley S, Cummings S. Designing clinical research. Baltimore: Williams and Wilkins; 1988;
  42. NdG Tyson. Signal versus noise. Natural History. 1996;105(10):72–76
  43. Wood G. Effect of antihypertensive agents on the arterial partial pressure of oxygen and venous admixture after cardiac surgery. Critical Care Medicine. 1997;25:1807–1812
  44. Morris A, Orme J, Truwit J, et al. A replicable method for blood glucose control in critically ill patients. Critical Care Medicine. 2008;36:1787–1795
  45. Campbell D, Stanley J. Experimental and quasi-experimental designs for research. (reprinted from handbook of research on teaching, 1963) Boston: Houghton Mifflin Co.; 1966;
  46. Babbie E. Observing ourselves: essays in social research. Belmont, Cal: Wadsworth Pub. Co.; 1986;
  47. Guyatt G, Sackett D, Cook D. User's guide to the medical literature: II. How to use an article about therapy or prevention; A. Are the results of the study valid?. JAMA: The Journal of the American Medical Association. 1993;270(21):2598–2601
  48. Guyatt G, Sackett D, Cook D. User's guide to the medical literature: II. How to use and article about therapy or prevention; B. What were the results and will they help me in caring for my patient?. JAMA: The Journal of the American Medical Association. 1994;271(1):59–63
  49. Justice AC, Covinsky KE, Berlin JA. Assessing the generalizability of prognostic information. Annals of Internal Medicine. Mar 16, 1999;130(6):515–524
  50. Emanuel EJ, Wendler D, Grady C. What makes clinical research ethical?. JAMA : The Journal of the American Medical Association. May 24-31, 2000;283(20):2701–2711
  51. Barrow JD. The book of nothing. New York: Pantheon Books; 2000;
  52. Hawe P, Shiell A, Riley T. Complex interventions: how “out of control” can a randomised controlled trial be?. British Medical Journal. June 26, 2004;328(7455):1561–1563
  53. Giancoli D. Physics. 3rd ed.. Englewood Cliffs, NJ: Prentice Hall; 1995;
  54. Babbie E. Survey research methods. Belmont, Cal: Wadsworth Publishing Co.; 1990;
  55. Pocock SJ. Clinical trials: a practical approach. New York, NY: John Wiley & Sons; 1983;
  56. Bailey RW. Human performance engineering. 3rd ed.. Upper Saddle River, NJ: Prentice Hall; 1996;
  57. Piantadosi S. Clinical trials - a methodologic perspective. New York: John Wiley & Sons, Inc.; 1997;
  58. Brook RH, McGlynn EA, Shekelle PG. Defining and measuring quality of care: a perspective from US researchers. International Journal for Quality in Health Care. Aug, 2000;12(4):281–295
  59. Hulley S, Cummings S, Warren S, et al. Designing clinical research. 2nd ed.. Philadelphia: Lippincott Williams and Wilkins; 2001;
  60. Sackett D, Haynes R, Guyatt G, Tugwell P. Clinical epidemiology: a basic science for clinical medicine. 2nd ed.. Boston: Little, Brown; 1991;
  61. Silverman W. Doing more good than harm. Annals of the New York Academy of Sciences. 1993;703:5–11
  62. In:  Warren K,  Mosteller F editor. Doing more good than harm: the evaluation of health care interventions. New York: The New York Academy of Sciences; 1993;
  63. Horwitz RI, Singer BH, Makuch RW, Viscoli CM. Can treatment that is helpful on average be harmful to some patients? A study of the conflicting information needs of clinical inquiry and drug regulation. Journal of Clinical Epidemiology. 1996;49(4):395–4001996/4
  64. Berwick DM. Disseminating innovations in health care. JAMA: The Journal of the American Medical Association. Apr 16, 2003;289(15):1969–1975
  65. Barach P, Berwick DM. Patient safety and the reliability of health care systems. Annals of Internal Medicine. Jun 17, 2003;138(12):997–998
  66. Sox HC. Improving patient care. Annals of Internal Medicine. Jun 17, 2003;138(12):996
  67. Corke CF, Stow PJ, Green DT, et al. How doctors discuss major interventions with high risk patients: an observational study. British Medical Journal. January 22, 2005;330(7484):182
  68. Berwick DM. My right knee. Annals of Internal Medicine. January 18, 2005;142(2):121–125
  69. Morris A, Wallace C, Menlove R, et al. Randomized clinical trial of pressure-controlled inverse ratio ventilation and extracorporeal CO2 removal for ARDS. [erratum 1994;149(3, Pt 1):838, Letters to the editor 1995;151(1):255–256, 1995;151(3):1269-1270, and 1997;156(3):1016-1017] American Journal of Respiratory and Critical Care Medicine. 1994;149(2):295–305
  70. East T, Heermann L, Bradshaw R, et al. Efficacy of computerized decision support for mechanical ventilation: results of a prospective multi-center randomized trial. Proceedings of AMIA Symposium. 1999;251–255
  71. The Acute Respiratory Distress Syndrome Network . Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The New England Journal of Medicine. 2000;342(18):1301–1308
  72. The Acute Respiratory distress Syndrome Network. Mechanical Ventilation Protocol (Complete). World wide Web: wwwardsnetorg or NAPS Document No 05542 (Microfiche Publications, 248 Hempstead Turnpike, West Hempstead, New York 11552). 2000.
  73. The National Heart Lung and Blood Institute Acute Respiratory Distress Syndrome Clinical Trials Network . Pulmonary-artery versus central venous catheter to guide treatment of acute lung injury. The New England Journal of Medicine. May 25, 2006;354(21):2213–2224
  74. The National Heart Lung and Blood Institute Acute Respiratory Distress Syndrome Clinical Trials Network . Comparison of two fluid-management strategies in acute lung injury. The New England Journal of Medicine. June 15, 2006;354(24):2564–2575
  75. Petty T. Pulmonary perspectives: the use, abuse, and mystique of positive end-expiratory pressure. The American Review of Respiratory Disease. 1988;138:475–478
  76. Shewart W. Economic control of quality of manufactured product. New York, NY: D. Van Nostrand Co., Inc; 1931;(republished in 1980, American Society for Quality Control, 230 W. Wells St, Milwaukee, Wisconsin 53203)
  77. Deming W. Quality, productivity, and competitive position. Cambridge: Mass: Massachusetts Institute of Technology, Center for Advanced Engineering Study; 1982;
  78. Deming W. Out of the crisis. Cambridge: Mass: Massachusetts Institute of Technology, Center for Advanced Engineering Study; 1986;
  79. Imai M. Kaizen-the key to Japan's competitive success. New York, NY: McGraw-Hill Publishing Company; 1986;
  80. Walton M. The Deming management method. New York: Putnam Publishing Group (Perigee books); 1986;
  81. James B, Horn S, Stephenson R. Management by fact: what is CPI and how is it used?. In:  Horn S,  Hopkins D editor. Clinical practice improvement: a new technology for developing cost-effective quality health care. New York: Faulker & Gray, Inc.; 1994;p. 39–54
  82. In:  Horn S,  Hopkins D editor. Clinical practice improvement: a new technology for developing cost-effective quality health care. New York: Faulker & Gray, Inc.; 1994;
  83. Berwick DM. Eleven worthy aims for clinical leadership of health system reform. JAMA: The Journal of the American Medical Association. 1994;272(10):797–802
  84. James BC, Hammond ME. The challenge of variation in medical practice. Archives of Pathology & Laboratory Medicine. Jul, 2000;24(7):1001–1003
  85. Thompson B, Orme J, Zheng H, et al. Multicenter validation of a computer-based clinical decision support tool for glucose control in adult and pediatric intensive care units. Journal of Diabetes Science and Technology (Online). May, 2008;2(3):357–368
  86. Pachler C, Plank J, Weinhandl H, et al. Tight glycaemic control by an automated algorithm with time-variant sampling in medical ICU patients. Intensive Care Medicine. Jul, 2008;34(7):1224–1230
  87. Vogelzang M, Loef BG, Regtien JG, et al. Computer-assisted glucose control in critically ill patients. Intensive Care Medicine. Aug, 2008;34(8):1421–1427
  88. Guidelines-Committee-Society-of-Critical-Care-Medicine . Guidelines for the care of patients with hemodynamic instability associated with sepsis. Critical Care Medicine. 1992;20(7):1057–1059
  89. Sheppard LC, Kouchoukos NT, Kurtis MA. Automated treatment of critically ill patients following operation. Annals of Surgery. 1968;168:596–604
  90. Blesser W. A systems approach to biomedicine. New York: McGraw-Hill Book Company; 1969;
  91. Sheppard L, Kirklin J, Kouchoukos N. Chapter 6-computer-controlled interventions for the acutely Ill patient. 1974.
  92. Sheppard L. Computer control of the infusion of vasoactive drugs. Annals of Biomedical Engineering. 1980;8(4–6):431–434
  93. East TD, Böhm SH, Wallace CJ, et al. A successful computerized protocol for clinical management of pressure control inverse ratio ventilation in ARDS patients. Chest. 1992;101(3):697–710
  94. Henderson S, Crapo R, Wallace C, et al. Performance of computerized protocols for the management of arterial oxygenation in an intensive care unit. International Journal of Clinical Monitoring and Computing. 1992;8:271–280
  95. Morris A. Evaluating and refining a hemodynamic protocol for use in a multicenter ARDS clincial trial. American Journal of Respiratory and Critical Care Medicine. 2000;161(3):A378;(ATS Proceedings Abstracts) Suppl
  96. Armstrong R, Bullen C, Cohen S, et al. Critical care algorithms. New York, NY: Oxford University Press; 1991;
  97. In:  Don H editors. Decision making in critical care. Philadelphia: BC Decker Inc.; 1985;
  98. Karlinsky J, Lau J, Goldstein R. Decision making in pulmonary medicine. Philadelphia: BC Decker; 1991;
  99. Miller R, Goodman K. Ethical challenges in the use of decision-support software in clinical practice. In:  Goodman K editors. Ethics, computing, and medicine: informatics and the transformation of health care. Cambridge, UK: Cambridge Univeristy Press; 1998;p. 102–115
  100. In:  Field M,  Lohr K editor. Clinical practice guidelines: directions for a new program (summary). Washington, D.C.: National Academy Press; 1990;
  101. Tierney WM, Overhage JM, Takesue BY, et al. Computerizing guidelines to improve care and patient outcomes: the example of heart failure. Journal of the American Medical Informatics Association. 1995;2(5):316–322
  102. Fridsma D, Gennari J, Musen M, editors. Making generic guidelines site-specific. Proceedings 1996 AMIA Annual Fall Symposium (Formerly SCAMC). Washington, D.C.: Hanley & Belfus, Inc.; 1996.
  103. Ely EW, Meade MO, Haponik EF, et al. Mechanical ventilator weaning protocols driven by nonphysician health-care professionals : evidence-based clinical practice guidelines. Chest. December 1, 2001;120(90060):454S–463S
  104. MacIntyre NR. Evidence-based guidelines for weaning and discontinuing ventilatory support : a collective task force facilitated by the american college of chest physicians; the american association for respiratory care; and the American college of critical care medicine. Chest. December 1, 2001;120(90060):375S–396S
  105. Audet A-M, Greenfield S, Field M. Medical practice guidelines: current activities and future directions. Annals of Internal Medicine. 1990;113:709–714
  106. Fletcher R, Fletcher S. Clinical practice guidelines. Annals of Internal Medicine. 1990;113:645–646
  107. Hadorn D, McCormick K, Diokno A. An annotated algorithm approach to clinical guideline development. JAMA: The Journal of the American Medical Association. 1992;267(24):3311–3314
  108. Miller P, Frawly S. Trade-offs in producing patient-specific recommendations from a computer-based clinical guideline: a case study. Journal of the American Medical Informatics Association. 1995;2:238–242
  109. Tierney WM, Overhage JM, McDonald CJ, editors. Computerizing guidelines: Factors for success. Proceedings 1996 AMIA Annual Fall Symposium (Formerly SCAMC). Washington, D.C.: Hanley & Belfus, Inc.; 1996.
  110. Flexner S. The random house dictionary of the English language. 2nd ed.. New York: Random House Inc.; 1987;
  111. McDonald CJ, Wilson GA, McCabe G. Physician response to computer reminders. JAMA : The Journal of the American Medical Association. 1980;244(14):1579–1581
  112. McDonald CJ, Hui SL, Tierney WM. Effects of computer reminders for influenza vaccination on morbidity during influenza epidemics. M.D. Computing: Computers in Medical Practice. 1992;9(5):304–312
  113. Evans RS, Pestotnik SL, Classen DC, et al. A computer-assisted management program for antibiotics and other antiinfective agents. The New England Journal of Medicine. 1998;338(4):232–238
  114. Garibaldi RA. Computers and the quality of care - a clinician's perspective. The New England Journal of Medicine. 1998;338(4):259–260
  115. Zielstorff R. Online practice guidelines: issues, obstacles, and future prospects. Journal of the American Medical Informatics Association. 1998;5(3):227–236
  116. McKinley BA, Moore FA, Sailors RM, et al. Computerized decision support for mechanical ventilation of trauma induced ARDS: results of a randomized clinical trial. The Journal of Trauma. Mar, 2001;50(3):415–424[discussion: 25]
  117. Hovorka R, Canonico V, Chassin LJ, et al. Nonlinear model predictive control of glucose concentration in subjects with type 1 diabetes. Physiological Measurement. Aug, 2004;25(4):905–920
  118. Holcomb BW, Wheeler AP, Ely EW. New ways to reduce unnecessary variation and improve outcomes in the intensive care unit. Current Opinion in Critical Care. 2001;7(4):304–311
  119. Morris A. Treatment algorithms and protocolized care. Current Opinion in Critical Care. June 1, 2003;9(3):236–240
  120. Grunberg SM, Cefalu WT. The integral role of clinical research in clinical care. The New England Journal of Medicine. April 3, 2003;348(14):1386–1388
  121. Steinbrook R. How best to ventilate? Trial design and patient safety in studies of the acute respiratory distress syndrome. The New England Journal of Medicine. April 3, 2003;348(14):1393–1401
  122. Drazen JM. Controlling research trials. The New England Journal of Medicine. April 3, 2003;348(14):1377–1380
  123. Reinertsen JL. Zen and the art of physician autonomy maintenance. Annals of Internal Medicine. Jun 17, 2003;138(12):992–995
  124. Clemmer TP. Computers in the ICU: where we started and where we are now. Journal of Critical Care. Dec, 2004;19(4):201–207
  125. East T. Computers in the ICU: panacea or plague?. Respiratory Care. 1992;37(2):170–180
  126. Morris A, East T, Wallace C, et al. Standardization of clinical decision making for the conduct fof credible clinical research in complicated medical environments. In: Proceedings of the 1996 AIMIA Annual Fall Symposium. 1996. pp. 418–422.
  127. Rood E, Bosman RJ, van der Spoel JI, et al. Use of a computerized guideline for glucose regulation in the intensive care unit improved both guideline adherence and glucose regulation. Journal of the American Medical Informatics Association. March 1, 2005;12(2):172–180
  128. Musen MA, Shahar Y, Shortliffe EH. Clinical decision-support systems. In:  Shortliffe EH,  Cimino JJ editor. Biomedical informatics: computer applications in health care and biomedicine. 3rd ed.. New York: Springer; 2006;p. 698–736
  129. Wiederhold G, Shortliffe EH. System design and engineering in health care. In:  Shortliffe EH,  Cimino JJ editor. Biomedical informatics: computer applications in health care and biomedicine. 3rd ed.. New York: Springer; 2006;p. 233–264
  130. Sorenson D, Grissom C, Carpenter L, et al. A frame-based representation for a bedside ventilation weaning protocol. Journal of Biomedical Informatics. 2008;41:461–468
  131. Grimm RH, Shimoni K, Harlan WR, Estes EH. Evaluation of patient-care protocol use by various providers. The New England Journal of Medicine. 1975;292:507–511
  132. Cannon SR, Gardner RM. Experience with a computerized interactive protocol system using HELP. Computers and Biomedical Research. 1980;13:399–409
  133. Wirtschafter DD, Scalise M, Henke C, Gams RA. Do information systems improve the quality of clinical research? Results of a randomized trial in a cooperative multi-institutional cancer group. Computers and Biomedical Research. 1981;14:78–90
  134. McDonald CJ, Hammond WF. Standard formats for electronic transfer of clinical data (editorial). Annals of Internal Medicine. 1989;110(5):333–335
  135. Johnston M, Langton K, Haynes B, Mathieu A. Effects of computer-based clinical decision support systems on clinician performance and patient outcome. Annals of Internal Medicine. 1994;120:135–142
  136. Lobach D, Hammon W. Computerized decision support based on a clinical practice guideline improves compliance with care standards. The American Journal of Medicine. 1997;102:89–98
  137. Shojana K, Yokoe D, Platt R, et al. Reducing Vancomcin use utilizing a computer guideline: results of a randomized controlled tral. Journal of the American Medical Informatics Association. 1998;5:554–562
  138. Weinstein M, Feinberg H. Clinical decision alalysis. Philadelphia: W.B. Saunders Co.; 1980;
  139. Bankowitz R, McNeil M, Challinor S, et al. A computer-assisted medical diagnostic consultation service: implementation and prospective evaluation of a prototype. Annals of Internal Medicine. 1989;110:824–832
  140. Lipsey M. Design sensitivity: statistical power for experimental research. Newbury Park, CA: Sage; 1990;
  141. Hennekens C, Buring J. Epidemiology in medicine. In:  Mayrent S editors. 1st ed.. Boston: Little, Brown and Company; 1987;
  142. Friedman LM, Furberg CD, DeMets DL. Fundamentals of clinical trials. 3rd ed.. New York: Springer-Verlag; 1998;
  143. Rothman K, Greenland S. Modern epidemiology. 2nd ed.. Philadelphia, Pennsylvania: Lippincott-Raven; 1998;
  144. Chow S-C, Liu J-P. Design and analysis of clinical trials. Hoboken: John Wiley & Sons, INc; 2004;
  145. Morris AH. Paradigms in management. In:  Pinsky M,  Dhainaut J editor. Pathophysiologic foundations of critical care medicine. Baltimore: Williams and Wilkens; 1993;p. 193–206
  146. Morris A, Cook D. Clinical trial issues in mechanical ventilation. In:  Marini J,  Slutsky A editor. Physiologic basis of ventilatory suport. New York: Marcel Dekker, Inc.; 1998;p. 1359–1398
  147. Frumin JR. Clinical use of a physiological respirator producing N2O amnesia-analgesia. Anesthesiology. 1957;18:290–299
  148. Coles JR, Brown WA, Lampard DG. Compter control of respiration and anesthesia. Medical & Biological Engineering. 1973;11:262–267
  149. East TD, Westenskow DR, Pace NL, Nelson LD. A microcomputer based differential lung ventilation system. IEEE Transactions on Bio-medical Engineering. 1982;736–740BME-29
  150. Chapman FW, Newell JC, Roy RJ. A feedback controller for ventilatory therapy. Annals of Biomedical Engineering. 1985;13:359–372
  151. East TD. Real-time data acquisition and control. In:  Shoemaker WC,  Abraham E editor. Diagnositc methods in critical care: automated data collection and interpretation. New York: Marcel Dekker; 1987;p. 285–310
  152. McDonald C, Tierney W. Computer-stored medical records-their future role in medical practice. JAMA : The Journal of the American Medical Association. 1988;259:3433–3440
  153. East TD, Tolle CR, Farrell RM, Brunner JX. A non-linear closed-loop controller for oxygenation based on a clinically proven fifth dimensional quality surface. Critical Care Medicine. 1991;19(4):S61
  154. Rubin J. Handbook of usability testing. New York: John Wiley & Sons; 1994;
  155. Morris A, Orme JJ, Clemmer T, et al. Hemodynamic computerized protocol development. American Journal of Respiratory and Critical Care Medicine. 1999;159(3):A84
  156. Sward K. Patterns of noncompliance with recommendations from a computerized insulin protocol [Ph.D. dissertation]. United States–Utah: The University of Utah, Available from ProQuest Digital Dissertations. Publication Number: AAT 3265845; 2007.
  157. Sward K, Orme JJ, Sorenson D, et al. Reasons for declining computerized insulin protocol recommendations: application of a framework. Journal of Biomedical Informatics. 2008;41:488–497
  158. Hayes-Roth F, Waterman D, Lenat D. An overview of expert systems. In:  Hayes-Roth F,  Waterman D,  Lenat D editor. Building expert systems. London. UK: Addison-Wesley Publishing Company, Inc.; 1983;p. 3–29
  159. East TD, Morris AH, Clemmer TP, et al. editors. Development of computerized critical care protocols -a strategy that really works. Proceedings of the fourteenth annual symposium on computer applications in medical care, Nov 1990. Washington, D.C.: IEEE Computer Soc Press, Los Alamitos, CA; 1990.
  160. East T, Henderson S, Pace N, et al. Knowledge engineering using retrospective review of data: a useful technique or merely data dredging?. International Journal of Clinical Monitoring and Computing. 1992;8:259–262
  161. Kinder A, East T, Littman W, et al. editors. A computerized decision support system for management of mechanical ventilation in patients with ARDS: An example of exportation of a knowledge base. Proceedings of the 17th Annual Symposium on Computer Applications in Medical Care. Washington, D.C.: McGraw-Hill, Inc.; 1993.
  162. Summers R, Carson E, Cramp D. Ventilator management: the role of knowledge-based technology. IEEE Engineering in Medicine and Biology. 1993;12(4):50–58
  163. Weed L. Reengineering medicine: questions and answers. Federation Bulletin. 1995;82(1):24–36
  164. Burgher C. The use of problem knowledge couplers in a primary care practice. Healthcare Information Management. 1997;11(4):13–26
  165. Weed LL, Weed L. Opening the black box of clinical judgment – an overview. BMJ (eBMJ edition). 13 November 1999; 319(7220):1279–1282 (Data Supplement: http://www.bmj.com/cgi/content/short/319/7220/1279/DC2).
  166. Sorenson D, Warner H. Generation and maintenance of ILIAD medical knowledge in a HyperCard environment. In: Proceedings of the 12th Annual Symposium on Computer Applications in Medical Care 1988.
  167. Morris AH. Computerized protocols to assist clinical research. In:  Olsen L,  Aisner D,  McGinnis JM editor. The learning healthcare system: workshop summary (roundtable on evidence-based medicine). Washington, DC: The National Academies Press; 2007;p. 1–19to 1–35
  168. Morris A. Hemodynamic guidelines. [see editorial: PC Gay. Of pundits, professors, and pollsters. Critical Care Medicine 1993;21(7):959–960] Critical Care Medicine. 1993;21(7):1096
  169. McDonald C, Overhage J. Guidelines you can follow and trust: an ideal and an example. JAMA : The Journal of the American Medical Association. 1994;271(11):872–873
  170. Courtney S, Durand D, Asselin J, et al. High-frequency oscillatory ventilation versus conventional mechanical ventilation for very-low-birth-weight infants. The New England Journal of Medicine. Aug 29, 2002;347(9):643–652
  171. Johnson AH, Peacock JL, Greenough A, et al. High-frequency oscillatory ventilation for the prevention of chronic lung disease of prematurity. The New England Journal of Medicine. Aug 29, 2002;347(9):633–642
  172. Stark A. High-frequency oscillatory ventilation to prevent bronchopulmonary dysplasia–are we there yet?. The New England Journal of Medicine. Aug 29, 2002;347(9):682–684
  173. Coffman S. Virginia Henderson international nursing library. Science on the loose. Reflectins. 1996;22(2):30
  174. Kuperman GJ, Bobb A, Payne TH, et al. Medication-related clinical decision support in computerized provider order entry systems: a review. Journal of the American Medical Informatics Association. Jan-Feb, 2007;14(1):29–40
  175. Niland JC, Rouse L, Stahl DC. An informatics blueprint for healthcare quality information systems. Journal of the American Medical Informatics Association. Jul-Aug, 2006;13(4):402–417
  176. Agrawal A, Mayo-Smith MF. Adherence to computerized clinical reminders in a large healthcare delivery network. Studies in Health Technology and Informatics. 2004;107(Pt 1):111–114
  177. Morris A, Orme J, Lee K, et al. Unusual insight from clinician compliance with a bedside computerized glucose/IV insulin infusion protocol. American Journal of Respiratory and Critical Care Medicine. 2006;A380;(Proc International American Thoracic Society meeting 2006)
  178. Beyth-Marom R, Dekel S. An elementary approach to thinking under uncertainty. Hillsdale, New Jersey: Lawrence Erlbaum Associates; 1985;
  179. Gilhooly K. Cognitive psychology and medical diagnosis. Applied Cognitive Psychology. 1990;4:261–272
  180. Norretranders T. The user illusion: cutting consciousness down to size. New York: Penguin Books; 1998;
  181. Klein JG. Five pitfalls in decisions about diagnosis and prescribing. British Medical Journal. April 2, 2005;330(7494):781–783
  182. Kurzweil R. The singularity is near - when humans transcend biology. New York: Viking Penguin; 2005;
  183. Friedman CP, Wyatt JC, Owens DK. Evaluation and technology assessment. In:  Shortliffe EH,  Cimino JJ editor. Biomedical informatics: computer applications in health care and biomedicine. 3rd ed.. New York: Springer; 2006;p. 403–443
  184. Brink P, Wood M. Advanced design in nursing research. 2nd ed.. Thousand Oaks: Sage; 1998;
  185. Burns N, Grove S. The practice of nursing research: conduct, critique, and utilization. 4th ed.. Philadelphia: WB Saunders; 2001;
  186. Kushniruk AW, Patel VL. Cognitive and usability engineering methods for the evaluation of clinical information systems. Journal of Biomedical Informatics. Feb, 2004;37(1):56–76
  187. Weiderhold G, Shortliffe E. System design and engineering. In:  Shortiffe E,  Perrault L editor. Medical informatics: computer applications in health care and biomedicine. 2nd ed.. New York: Springer; 2001;

 Supported in part by the NIH (RO1-HL-36787, NO1-HR-46062), the AHCPR (HS 06594) the Deseret Foundation, the Respiratory Distress Syndrome Foundation, the LDS Hospital, the Deseret Foundation, and by Intermountain Healthcare, Inc.

PII: S1521-6896(08)00084-0

doi: 10.1016/j.bpa.2008.09.002

Best Practice & Research Clinical Anaesthesiology
Volume 23, Issue 1 , Pages 51-67 , March 2009