Best Practice & Research Clinical Anaesthesiology
Volume 22, Issue 4 , Pages 645-657, December 2008

Perioperative complications of hypothermia

  • Andrea Kurz, MD (Vice Chair, Professor of Anesthesiology)

      Affiliations

    • Corresponding Author InformationCorresponding author. Department of Outcomes Research, Anesthesia Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, 44195 OH, USA. Tel.: +1 216 445 9924; Fax: +1 216 444 6235.

Department of Outcomes Research, Anesthesia Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA

Cleveland Clinic Lerner College of Medicine, Cleveland, 44195 OH, USA

Department of Outcomes Research, Anesthesia Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA

Department of Outcomes Research, Anesthesia Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA

Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44195, USA

Perioperative hypothermia is a common and serious complication of anesthesia and surgery and is associated with many adverse perioperative outcomes. It prolongs the duration of action of inhaled and intravenous anesthetics as well as the duration of action of neuromuscular drugs. Mild core hypothermia increases thermal discomfort, and is associated with delayed post anaesthetic recovery. Mild hypothermia significantly increases perioperative blood loss and augments allogeneic transfusion requirement. Only 1.9°C core hypothermia triples the incidence of surgical wound infection following colon resection and increases the duration of hospitalization by 20%. Hypothermia adversely affects antibody- and cell-mediated immune defences, as well as the oxygen availability in the peripheral wound tissues. Furthermore mild hypothermia triples the incidence of postoperative adverse myocardial events. Thus, even mild hypothermia contributes significantly to patient care costs and needs to be avoided.

Key words: anaesthesia, hypothermia, complication, perioperative, temperature, thermoregulation

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PII: S1521-6896(08)00061-X

doi:10.1016/j.bpa.2008.07.005

Best Practice & Research Clinical Anaesthesiology
Volume 22, Issue 4 , Pages 645-657, December 2008