Best Practice & Research Clinical Anaesthesiology
Volume 22, Issue 4 , Pages 627-644 , December 2008

Physiology of Thermoregulation

  • Andrea Kurz, M.D. (Professor and Vice Chair)

      Affiliations

    • Corresponding Author InformationTel.: +1 216 445 9924; Fax: +1 216 444 6135.

References 

  1. Satinoff E. Neural organization and evolution of thermal regulation in mammals – several hierarchically arranged integrating systems may have evolved to achieve precise thermoregulation. Science. 1978;201:16–22
  2. Jessen C, Feistkorn G. Some characteristics of core temperature signals in the conscious goat. American Journal of Physiology. 1984;247:R456–R464
  3. Shomaker TS, Bjoraker DG. Measurement offset with liquid crystal temperature indicators (abstract). Anesthesiology. 1990;73:A425
  4. Marks LI, Gonzalez RR. Skin temperature modfies the pleasantness of thermal stimuli. Nature. 1974;247:473–475
  5. Lopez M, Sessler DI, Walter K, et al. Rate and gender dependence of the sweating, vasoconstriction, and shivering thresholds in humans. Anesthesiology. 1994;80:780–788
  6. Vassilieff N, Rosencher N, Sessler DI, et al. The shivering threshold during spinal anesthesia is reduced in the elderly. Anesthesiology. 1995;83:1162–1166
  7. Buono MJ, Sjoholm NT. Effect of physical training on peripheral sweat production. Journal of Applied Physiology. 1988;65:811–814
  8. Detry J-MR, Brengelmann GL, Rowell LB, et al. Skin and muscle components of forearm blood flow in directly heated resting man. Journal of Applied Physiology. 1972;32:506–511
  9. Flavahan NA. The role of vascular alpha-2-adrenoceptors as cutaneous thermosensors. News in Physiological Sciences. 1991;6:251–255
  10. Hales JRS. Skin arteriovenous anastomoses, their control and role in thermoregulation. In:  Johansen K,  Burggren W editor. Cardiovascular Shunts: Phylogenetic, Ontogenetic and Clinical Aspects. Copenhagen: Munksgaard; 1985;p. 433–451
  11. Dawkins MJR, Scopes JW. Non-shivering thermogenesis and brown adipose tissue in the human new-born infant. Nature. 1965;206:201–202
  12. Brück K, Baum E, Schwennicke HP. Cold-adapative modifications in man induced by repeated short-term cod-exposures and during a 10-day and -night cold-exposure. Pflügers Archiv. 1976;363:125–133
  13. Takahashi H, Nakamura S, Shirahase H, et al. Heterogenous activity on BRL 35135, a ß3-adrenoceptor agonist, in thermogenesis and increased blood flow in brown adipose tissue in anaesthetized rats. Clinical and Experimental Pharmacology & Physiology. 1994;21:539–543
  14. Ricquier R, Casteilla L, Bouillaud F. Molecular studies of the uncoupling protein. FASEB Journal. 1991;5:2237–2242
  15. Just B, Delva E, Camus Y, et al. Oxygen uptake during recovery following naloxone. Anesthesiology. 1992;76:60–64
  16. Kurz A, Go JC, Sessler DI, et al. Alfentanil slightly increases the sweating threshold and markedly reduces the vasoconstriction and shivering thresholds. Anesthesiology. 1995;83:293–299
  17. Matsukawa T, Kurz A, Sessler DI, et al. Propofol linearly reduces the vasoconstriction and shivering thresholds. Anesthesiology. 1995;82:1169–1180
  18. Xiong J, Kurz A, Sessler DI, et al. Isoflurane produces marked and non-linear decreases in the vasoconstriction and shivering thresholds. Anesthesiology. 1996;85:240–245
  19. Annadata RS, Sessler DI, Tayefeh F, et al. Desflurane slightly increases the sweating threshold, but produces marked, non-linear decreases in the vasoconstriction and shivering thresholds. Anesthesiology. 1995;83:1205–1211
  20. Kurz A, Sessler DI, Annadata R, et al. Midazolam minimally impairs thermoregulatory control. Anesthesia and Analgesia. 1995;81:393–398
  21. Bissonnette B, Sessler DI. Thermoregulatory thresholds for vasoconstriction in pediatric patients anesthetized with halothane or halothane and caudal bupivacaine. Anesthesiology. 1992;76:387–392
  22. Sessler DI, Hynson J, McGuire J, et al. Thermoregulatory vasoconstriction during isoflurane anesthesia minimally decreases heat loss. Anesthesiology. 1992;76:670–675
  23. Washington D, Sessler DI, Moayeri A, et al. Thermoregulatory responses to hyperthermia during isoflurane anesthesia in humans. Journal of Applied Physiology. 1993;74:82–87
  24. Kurz A, Xiong J, Sessler DI, et al. Desflurane reduces the gain of thermoregulatory arterio-venous shunt vasoconstriction in humans. Anesthesiology. 1995;83:1212–1219
  25. Cheng C, Matsukawa T, Sessler DI, et al. Increasing mean skin temperature linearly reduces the core-temperature thresholds for vasoconstriction and shivering in humans. Anesthesiology. 1995;82:1160–1168
  26. Matsukawa T, Sessler DI, Sessler AM, et al. Heat flow and distribution during induction of general anesthesia. Anesthesiology. 1995;82:662–673
  27. Hynson JM, Sessler DI, Moayeri A, et al. The effects of pre-induction warming on temperature and blood pressure during propofol/nitrous oxide anesthesia. Anesthesiology. 1993;79:219–228
  28. Kurz A, Sessler DI, Christensen R, et al. Heat balance and distribution during the core-temperature plateau in anesthetized humans. Anesthesiology. 1995;83:491–499
  29. Kurz A, Sessler DI, Narzt E, et al. Morphometric influences on intraoperative core temperature changes. Anesthesia and Analgesia. 1995;80:562–567
  30. Kurz A, Sessler DI, Schroeder M, et al. Thermoregulatory response thresholds during spinal anesthesia. Anesthesia and Analgesia. 1993;77:721–726
  31. Matsukawa T, Sessler DI, Christensen R, et al. Heat flow and distribution during epidural anesthesia. Anesthesiology. 1995;83:961–967
  32. Leslie K, Sessler DI. Reduction in the shivering threshold is proportional to spinal block height. Anesthesiology. 1996;84:1327–1331
  33. Sessler DI, Ponte J. Shivering during epidural anesthesia. Anesthesiology. 1990;72:816–821
  34. Glosten B, Sessler DI, Faure EAM, et al. Central temperature changes are not perceived during epidural anesthesia. Anesthesiology. 1992;77:10–16
  35. Bredahl C, Hindsholm KB, Frandsen PC. Changes in body heat during hip fracture surgery: A comparison of spinal analgesia and general anesthesia. Acta Anaesthesiologica Scandinavica. 1991;35:548–552
  36. Shimosato S, Etsten BE. The role of the venous system in cardiocirculatory dynamics during spinal and epidural anesthesia in man. Anesthesiology. 1969;30:619–628
  37. Sharkey A, Lipton JM, Murphy MT, et al. Inhibition of postanesthetic shivering with radiant heat. Anesthesiology. 1987;66:249–252
  38. Capogna G, Celleno DIV. Clonidine for post-extradural shivering in parturients: a preliminary study. British Journal of Anaesthesia. 1993;71:29–295
  39. Guffin A, Girard D, Kaplan JA. Shivering following cardiac surgery: Hemodynamic changes and reversal. Journal of Cardiothoracic and Vascular Anesthesia. 1987;1:24–28
  40. Kurz M, Belani K, Sessler DI, et al. Naloxone, meperidine, and shivering. Anesthesiology. 1993;79:1193–1201

PII: S1521-6896(08)00055-4

doi: 10.1016/j.bpa.2008.06.004

Best Practice & Research Clinical Anaesthesiology
Volume 22, Issue 4 , Pages 627-644 , December 2008