Best Practice & Research Clinical Anaesthesiology
Volume 22, Issue 2 , Pages 359-368, June 2008

Arginine vasopressin vs. terlipressin in the treatment of shock states

  • Mervyn Singer, MBBS, MD, FRCP(Lon), FRCP(Edin) (Professor of Intensive Care Medicine)

      Affiliations

    • Corresponding Author InformationTel.: +44 207 679 6714; Fax: +44 207 679 6952.

Bloomsbury Institute of Intensive Care Medicine, University College London, Cruciform Building, Gower Street, London WC1E 6BT, United Kingdom

The synthetic vasopressin analogue, terlipressin, is being increasingly used to treat catecholamine-resistant hypotension in septic shock and other conditions. While terlipressin holds some theoretical and anecdotal advantages over vasopressin, this has not been formally tested in prospective randomised trials. This review analyses the published literature and makes comparisons, where possible, between vasopressin and terlipressin.

Key words: terlipressin, vasopressin, shock, septic shock, vascular hyporeactivity

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PII: S1521-6896(08)00029-3

doi:10.1016/j.bpa.2008.03.005

Best Practice & Research Clinical Anaesthesiology
Volume 22, Issue 2 , Pages 359-368, June 2008

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