Best Practice & Research Clinical Anaesthesiology
Volume 22, Issue 2 , Pages 351-358 , June 2008

Impact of vasopressin analogues on the gut mucosal microcirculation

  • Pierre Asfar, MD, PhD (Professor)

      Affiliations

    • Corresponding Author InformationCorresponding author. Département de Réanimation Médicale, CHU, Angers 49933 Cedex 9, France. Tel.: +33 2 41 35 38 15; Fax: +33 2 41 35 40 83.
  • Hendrik Bracht, MD, PhD (Doctor)

      Affiliations

    • Tel.: +49 731 500 60214; Fax: +49 731 500 60162.
    • ,
  • Peter Radermacher, MD, PhD (Professor)

      Affiliations

    • Tel.: +49 731 500 60214; Fax: +49 731 500 60162.

References 

  1. Landry DW, Oliver JA. The pathogenesis of vasodilatory shock. The New England Journal of Medicine. 2001;345:588–595
  2. Hassoun HT, Kone BC, Mercer DW, et al. Post-injury multiple organ failure: the role of the gut. Shock. 2001;15:1–10
  3. Reilly PM, Wilkins KB, Fuh KC, et al. The mesenteric haemodynamic response to circulatory shock: an overview. Shock. 2001;15:329–343
  4. Schmid PG, Abboud FM, Wendling MG, et al. Regional vascular effects of vasopressin: plasma levels and circulatory responses. American Journal of Physiology. 1974;227:998–1004
  5. Garcia-Villalon AL, Garcia JL, Fernandez N, et al. Regional differences in the arterial response to vasopressin: role of endothelial nitric oxide. British Journal of Pharmacology. 1996;118:1848–1854
  6. Laszlo F, Karacsony G, Pavo I, et al. Aggressive role of vasopressin in development of different gastric lesions in rats. European Journal of Pharmacology. 1994;258:15–22
  7. Laszlo F, Whittle BJ. Constitutive nitric oxide modulates the injurious actions of vasopressin on rat intestinal microcirculation in acute endotoxaemia. European Journal of Pharmacology. 1994;260:265–268
  8. Asfar P, Pierrot M, Veal N, et al. Low-dose terlipressin improves systemic and splanchnic haemodynamics in fluid-challenged endotoxic rats. Critical Care Medicine. 2003;31:215–220
  9. Martikainen TJ, Tenhunen JJ, Uusaro A, Ruokonen E. The effects of vasopressin on systemic and splanchnic haemodynamics and metabolism in endotoxin shock. Anesthesia and Analgesia. 2003;97:1756–1763
  10. Guzman JA, Rosado AE, Kruse JA. Vasopressin vs norepinephrine in endotoxic shock: systemic, renal, and splanchnic haemodynamic and oxygen transport effects. Journal of Applied Physiology. 2003;95:803–809
  11. Hiltebrand LB, Krejci V, Jakob SM, et al. Effects of vasopressin on microcirculatory blood flow in the gastrointestinal tract in anesthetized pigs in septic shock. Anesthesiology. 2007;106:1156–1167
  12. Sun Q, Dimopoulos G, Nguyen DN, et al. Low-dose vasopressin in the treatment of septic shock in sheep. American Journal of Respiratory and Critical Care Medicine. 2003;168:481–486Epub 2003 Jun 5
  13. Asfar P, Hauser B, Ivanyi Z, et al. Low-dose terlipressin during long-term hyperdynamic porcine endotoxemia: effects on hepatosplanchnic perfusion, oxygen exchange, and metabolism. Critical Care Medicine. 2005;33:373–380
  14. Martikainen TJ, Uusaro A, Tenhunen JJ, Ruokonen E. Dobutamine compensates deleterious haemodynamic and metabolic effects of vasopressin in the splanchnic region in endotoxin shock. Acta Anaesthesiologica Scandinavica. 2004;48:935–943
  15. Malay MB, Ashton JL, Dahl K, et al. Heterogeneity of the vasoconstrictor effect of vasopressin in septic shock. Critical Care Medicine. 2004;32:1327–1331
  16. Bennett T, Mahajan RP, March JE, et al. Regional and temporal changes in cardiovascular responses to norepinephrine and vasopressin during continuous infusion of lipopolysaccharide in conscious rats. British Journal of Anaesthesia. 2004;93:400–407
  17. Westphal M, Freise H, Kehrel BE, et al. Arginine vasopressin compromises gut mucosal microcirculation in septic rats. Critical Care Medicine. 2004;32:194–200
  18. Knotzer H, Maier S, Dunser MW, et al. Arginine vasopressin does not alter mucosal tissue oxygen tension and oxygen supply in an acute endotoxemic pig model. Intensive Care Medicine. 2006;32:170–174
  19. Knotzer H, Pajk W, Maier S, et al. Arginine vasopressin reduces intestinal oxygen supply and mucosal tissue oxygen tension. American Journal of Physiology. Heart and Circulatory Physiology. 2005;289:H168–H173
  20. Landry DW, Levin HR, Gallant EM, et al. Vasopressin deficiency contributes to the vasodilation of septic shock. Circulation. 1997;95:1122–1125
  21. Malay MB, Ashton RC, Landry DW, Townsend RN. Low-dose vasopressin in the treatment of vasodilatory septic shock. The Journal of Trauma. 1999;47:699–703
  22. Holmes CL, Walley KR, Chittock DR, et al. The effects of vasopressin on haemodynamics and renal function in severe septic shock: a case series. Intensive Care Medicine. 2001;27:1416–1421
  23. Patel BM, Chittock DR, Russell JA, Walley KR. Beneficial effects of short-term vasopressin infusion during severe septic shock. Anesthesiology. 2002;96:576–582
  24. O'Brien A, Clapp L, Singer M. Terlipressin for norepinephrine-resistant septic shock. Lancet. 2002;359:1209–1210
  25. Dunser MW, Mayr AJ, Ulmer H, et al. Arginine vasopressin in advanced vasodilatory shock: a prospective, randomized, controlled study. Circulation. 2003;107:2313–2319Epub 2003 May 5
  26. Leone M, Albanese J, Delmas A, et al. Terlipressin in catecholamine-resistant septic shock patients. Shock. 2004;22:314–319
  27. Lauzier F, Levy B, Lamarre P, Lesur O. Vasopressin or norepinephrine in early hyperdynamic septic shock: a randomized clinical trial. Intensive Care Medicine. 2006;32:1782–1789
  28. Klinzing S, Simon M, Reinhart K, et al. High-dose vasopressin is not superior to norepinephrine in septic shock. Critical Care Medicine. 2003;31:2646–2650
  29. Creteur J, De Backer D, Vincent JL. Does gastric tonometry monitor splanchnic perfusion?. Critical Care Medicine. 1999;27:2480–2484
  30. Morelli A, Rocco M, Conti G, et al. Effects of terlipressin on systemic and regional haemodynamics in catecholamine-treated hyperkinetic septic shock. Intensive Care Medicine. 2004;30:597–604

PII: S1521-6896(08)00023-2

doi: 10.1016/j.bpa.2008.02.009

Best Practice & Research Clinical Anaesthesiology
Volume 22, Issue 2 , Pages 351-358 , June 2008

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