Best Practice & Research Clinical Anaesthesiology
Volume 22, Issue 2 , Pages 317-321 , June 2008

“Terlipressin in the treatment of septic shock: the earlier the better?”

  • Andrea Morelli, MD (Assistant Professor)

      Affiliations

    • Corresponding Author InformationCorresponding author. Department of Anaesthesiology and Intensive Care, University of Rome, “La Sapienza”, Via B. Oriani 2, I-00197 Rome, Italy. Tel.: +390649978001; Fax: +39064461967.

References 

  1. Westphal M, Stubbe H, Sielenkamper AW, et al. Terlipressin dose response in healthy and endotoxemic sheep: impact on cardiopulmonary performance and global oxygen transport. Intensive Care Medicine. 2003;29:301–308
  2. O'Brien A, Clapp L, Singer M. Terlipressin for norepinephrine-resistant septic shock. The Lancet. 2002;359:1209–1210
  3. Morelli A, Rocco M, Conti G, et al. Effects of terlipressin on systemic and regional haemodynamics in catecholamine-treated hyperkinetic septic shock. Intensive Care Medicine. 2004;30:597–604
  4. Leone M, Albanese J, Delmas A, et al. Terlipressin in catecholamine-resistant septic shock patients. Shock. 2004;22:314–319
  5. Albanese J, Leone M, Delmas A, Martin C. Terlipressin or norepinephrine in hyperdynamic septic shock: a prospective, randomized study. Critical Care Medicine. 2005;33:1897–1902
  6. Morelli A, Ertmer C, Lange M, Westphal M. Continuous terlipressin infusion in patients with septic shock: less may be best, and the earlier the better?. Intensive Care Medicine. 2007;33:1669–1670
  7. Rivers E, Nguyen B, Havstad S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. The New England Journal of Medicine. 2001;345:1368–1377
  8. Rivers EP, Kruse JA, Jacobsen G, et al. The influence of early hemodynamic optimization on biomarker patterns of severe sepsis and septic shock. Critical Care Medicine. 2007;35:2016–2024
  9. Russell JA, Walley KR, Singer J, et al., the VASST Investigators  Vasopressin versus norepinephrine infusion in patients with septic shock. N Eng J Med. 2008;358:877–887
  10. Vincent JL. The International Sepsis Forum's frontiers in sepsis: high cardiac output should be maintained in severe sepsis. Critical Care. 2003;7:276–278
  11. Sharma VK, Dellinger RP. The International Sepsis Forum's frontiers in sepsis: high cardiac output should not be maintained in severe sepsis. Critical Care. 2003;7:272–275
  12. Lange M, Koehler G, Morelli A, et al. Continuous versus bolus infusion of terlipressin in ovine endotoxemia. Shock. 2007;28:623–629
  13. Jolley DH, De Keulenaer BL, Potter A, et al. Terlipressin infusion in catecholamine-resistant shock. Anaesthesia and Intensive Care. 2003;31:560–564
  14. Umgelter A, Reindl W, Schmid RM, et al. Continuous terlipressin infusion in patients with persistent septic shock and cirrhosis of the liver. Intensive Care Medicine. 2008;34:390–391

PII: S1521-6896(08)00020-7

doi: 10.1016/j.bpa.2008.02.006

Best Practice & Research Clinical Anaesthesiology
Volume 22, Issue 2 , Pages 317-321 , June 2008

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