Best Practice & Research Clinical Anaesthesiology
Volume 21, Issue 2 , Pages 195-208 , June 2007

The impact of storage on red cell function in blood transfusion

  • Can Ince, PhD (Professor of Clinical Physiology)

      Affiliations

    • Corresponding Author InformationCorresponding author.

References 

  1. Cabrales P, Tsai AG. Plasma viscosity regulates systemic and microvascular perfusion during acute extreme anemic conditions. American Journal of Physiology. Heart and Circulatory. 2006;291(5):H2445–H2452
  2. Cabrales P, Martini J, Intaglietta M, Tsai AG. Blood viscosity maintains microvascular conditions during normovolemic anemia independent of blood oxygen-carrying capacity. American Journal of Physiology. Heart and Circulatory. 2006;291(2):H581–H590
  3. Shonat RD, Johnson PC. Oxygen tension gradients and heterogeneity in venous microcirculation: a phosphorescence quenching study. The American Journal of Physiology. 1997;272(5 Pt 2):H2233–H2240
  4. Ellsworth ML. The red blood cell as an oxygen sensor: what is the evidence?. Acta Physiologica Scandinavica. 2000;168(4):551–559[Review]
  5. Dietrich HH, Ellsworth ML, Sprague RS, Dacey RG. Red blood cell regulation of microvascular tone through adenosine triphosphate. American Journal of Physiology. Heart and Circulatory. 2000;278(4):H1294–H1298
  6. Crawford JH, Isbell TS, Huang Z, et al. Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation. Blood. 2006;15;107(2):566–574
  7. Cosby K, Partovi KS, Crawford JH, et al. Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation. Nature Medicine. 2003;9(12):1498–1505
  8. Kleinbongard P, Schulz R, Rassaf T, et al. Red blood cells express a functional endothelial nitric oxide synthase. Blood. 2006;107(7):2943–2951
  9. Sprague RS, Ellsworth ML, Stephenson AH, et al. Deformation-induced ATP release from red blood cells requires CFTR activity. The American Journal of Physiology. 1998;275(5 Pt 2):H1726–H1732
  10. Jagger JE, Bateman RM, Ellsworth ML, Ellis CG. Role of erythrocyte in regulating local O2 delivery mediated by hemoglobin oxygenation. American Journal of Physiology. Heart and Circulatory. 2001;280(6):H2833–H2839
  11. Jia L, Bonaventura C, Bonaventura J, Stamler JS. S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control. Nature. 1996;380:221–226
  12. Schechter AN, Gladwin MT. Hemoglobin and the paracrine and endocrine functions of nitric oxide. The New England Journal of Medicine. 2003;348:1483–1485
  13. Wolfe LC. The membrane and the lesions of storage in preserved red cells. Transfusion. 1985;25(3):185–203[Review]
  14. Card RT. Red cell membrane changes during storage. Transfusion Medicine Reviews. 1988;2:40–47
  15. Hess JR, Greenwalt TJ. Storage of red blood cells: New approaches. Transfusion Medicine Reviews. 2002;16:283–295
  16. Rumsby MG, Trotter J, Allan D, Michell RH. Recovery of membrane micro-vesicles from human erythrocytes stored for transfusion: a mechanism for the erythrocyte discocyte-to-spherocyte shape transformation. Biochemical Society Transactions. 1977;5(1):126–128
  17. Brunauer LS, Moxness MS, Huestis WH. Hydrogen peroxide oxidation induces the transfer of phospholipids from the membrane into the cytosol of human erythrocytes. Biochemistry. 1994;33(15):4527–4532
  18. Verhoeven AJ, Hilarius PM, Dekkers DW, et al. Prolonged storage of red blood cells affects aminophospholipid translocase activity. Vox Sanguinis. 2006;91(3):244–251
  19. Sparrow RL, Healey G, Patton KA, Veale MF. Red blood cell age determines the impact of storage and leukocyte burden on cell adhesion molecules, glycophorin A and the release of annexin V. Transfusion and Apheresis Science. 2006 Feb;34(1):15–23
  20. Anniss AM, Sparrow RL. Expression of CD47 (integrin-associated protein) decreases on red blood cells during storage. Transfusion and Apheresis Science. 2002 Dec;27(3):233–238
  21. Bessos H, Seghatchian J. Red cell storage lesion: the potential impact of storage-induced CD47 decline on immunomodulation and the survival of leucofiltered red cells. Transfusion and Apheresis Science. 2005 Apr;32(2):227–232
  22. Heaton A, Keegan T, Holme S. In vivo regeneration of red cell 2,3-diphosphoglycerate following transfusion of DPG-depleted AS-1, AS-3 and CPDA-1 red cells. British Journal of Haematology. 1989;71(1):131–136
  23. d'Almeida MS, Gray D, Martin C, et al. Effect of prophylactic transfusion of stored red blood cells on oxygen reserve in response to acute isovolemic hemorrhage in a rodent model. Transfusion. 2001 Jul;41(7):950–956
  24. Raat NJ, Verhoeven AJ, Mik EG, et al. The effect of storage time of human red cells on intestinal microcirculatory oxygenation in a rat isovolemic exchange model. Critical Care Medicine. 2005;33(1):39–45[discussion 238–239]
  25. Hamasaki N, Yamamoto M. Red blood cell function and blood storage. Vox Sanguinis. 2000;79(4):191–197[Review]
  26. Fitzgerald RD, Martin CM, Dietz GE, et al. Transfusing red blood cells stored in citrate phosphate dextrose adenine-1 for 28 days fails to improve tissue oxygenation in rats. Critical Care Medicine. 1997;25(5):726–732
  27. van Bommel J, de Korte D, Lind A, et al. The effect of the transfusion of stored red blood cells on intestinal microvascular oxygenation in the rat. Transfusion. 2001;41(12):1515–1523
  28. Marik PE, Sibbald WJ. Effect of stored-blood transfusion on oxygen delivery in patients with sepsis. JAMA: The Journal of the American Medical Association. 1993;269:3024–3029
  29. Purdy FR, Tweeddale MG, Merrick PM. Association of mortality with age of blood transfused in septic ICU patients. Canadian Journal of Anaesthesia. 1997;44(12):1256–1261
  30. Basran S, Frumento RJ, Cohen A, et al. The association between duration of storage of transfused red blood cells and morbidity and mortality after reoperative cardiac surgery. Anesthesia and Analgesia. 2006 Jul;103(1):15–20
  31. Vamvakas EC, Carven JH. Length of storage of transfused red cells and postoperative morbidity in patients undergoing coronary artery bypass graft surgery. Transfusion. 2000;40:101–109
  32. Walsh TS, McArdle F, McLellan SA, et al. Does the storage time of transfused red blood cells influence regional or global indexes of tissue oxygenation in anemic critically ill patients?. Critical Care Medicine. 2004;32:364–371
  33. van de Watering L, Lorinser J, Versteegh M, et al. Effects of storage time of red blood cell transfusions on the prognosis of coronary artery bypass graft patients. Transfusion. 2006;46(10):1712–1718
  34. Corwin HL, Gettinger A, Pearl RG, et al. The CRIT Study: anemia and blood transfusion in the critically ill — current clinical practice in the United States. Critical Care Medicine. 2004;32:39–52
  35. Vincent JL, Baron JF, Reinhart K, et al. Anemia and blood transfusion in critically ill patients. JAMA: The Journal of the American Medical Association. 2002;288:1499–1507
  36. Raat NJ, Berends F, Verhoeven AJ, et al. The age of stored red blood cell concentrates at the time of transfusion. Transfusion Medicine (Oxford, England). 2005;15(5):419–423
  37. Izbicki G, Rudensky B, Na'amad M, et al. Transfusion-related leukocytosis in critically ill patients. Critical Care Medicine. 2004;32(2):439–442
  38. Bilgin YM, van de Watering LM, Eijsman L, et al. Double-blind, randomized controlled trial on the effect of leukocyte-depleted erythrocyte transfusions in cardiac valve surgery. Circulation. 2004;109(22):2755–2760
  39. Fung MK, Rao N, Rice J, et al. Leukoreduction in the setting of open heart surgery: A prospective cohort-controlled study. Transfusion. 2004;44:30–35
  40. Fung MK, Moore K, Ridenour M, et al. Clinical effects of reverting from leukoreduced to nonleukoreduced blood in cardiac surgery. Transfusion. 2006;46(3):386–391
  41. van de Watering LM, Hermans J, Houbiers JG, et al. Beneficial effects of leukocyte depletion of transfused blood on postoperative complications in patients undergoing cardiac surgery: a randomized clinical trial. Circulation. 1998;97(6):562–568
  42. Anniss AM, Sparrow RL. Storage duration and white blood cell content of red blood cell (red blood cell) products increases adhesion of stored red blood cells to endothelium under flow conditions. Transfusion. 2006;46(9):1561–1567
  43. Carroll J, Raththagala M, Subasinghe W, et al. An altered oxidant defense system in red blood cells affects their ability to release nitric oxide-stimulating ATP. Molecular BioSystems. 2006;2(6-7):305–311

PII: S1521-6896(07)00004-3

doi: 10.1016/j.bpa.2007.01.004

Best Practice & Research Clinical Anaesthesiology
Volume 21, Issue 2 , Pages 195-208 , June 2007